Listen "334.How Your Microbiome Controls Your Health with Leo Grady, Founder and CEO of Jona"
Episode Synopsis
Could your gut be the key to solving chronic fatigue, autoimmune issues, or even mental health? Leo Grady, Founder and CEO of Jona, joins the show to explain how AI is unlocking the secrets of the microbiome one stool sample at a time.From fecal transplants to personalized diet plans, learn how deep sequencing and transparent science are changing healthcare without the guesswork. Stream the episode and take control of your health from the inside out.Episode Breakdown0:00 – Why the gut microbiome is the missing key to modern medicine 1:00 – Meet Leo Grady, Founder and CEO of Jona: from AI in radiology to founding Jona Health 2:30 – The moment AI met biology: how data revealed the gut’s hidden power 4:00 – Why chronic disease, obesity, and inflammation start in the microbiome 6:00 – Building an AI model for the human gut: challenges and breakthroughs 8:30 – From Siemens Healthineers to Jona: Leo’s leap into microbiome medicine 10:00 – The science behind poop transplants and what they teach us 12:00 – How diet, stress, and sleep rewrite your gut ecosystem 14:30 – Using sequencing data and AI to personalize nutrition 17:00 – What a Jona test actually measures and how results are delivered 19:00 – Breaking down the gut report: good vs. bad bacteria explained 21:00 – How AI analyzes 2,000+ new gut studies each month 23:00 – Key biomarkers linked to fatigue, weight gain, and brain fog 25:00 – Microbiome diversity: why it matters more than calories 27:00 – The gut-brain connection: mood, dopamine, and serotonin 29:00 – Why most gut testing companies get the science wrong 31:00 – Lessons learned from the uBiome collapse and regaining trust 33:00 – Building a medical-grade company in the consumer health space 35:00 – The new wave of evidence-based biohacking 37:00 – AI vs. traditional medicine: merging two worlds of care 39:00 – Surprising discoveries from Jona’s real-world patient data 41:00 – How antibiotics, fasting, and fiber affect the microbiome 43:00 – The gut as your body’s sensory organ: interpreting internal signals 45:00 – Top foods that rebuild the microbiome naturally 47:00 – How wearables and gut data together unlock holistic health 49:00 – Leo’s daily health stack: protein, recovery, and AI tracking 51:00 – Final insights: why the microbiome revolution is just beginning 52:00 – Outro: subscribe, share, and take control of your gut healthAre you a medtech CEO in need of some marketing help attracting investors, growing sales pipeline, and more? Go to GrowMyMedtech.com to book time for a free analysis.Subscribe to our Youtube Channelhttps://www.youtube.com/channel/UCGpL_rGt1LQJwinMq_K7gfgSubscribe to our LinkedIn Newsletterhttps://www.stateofmedtechpodcast.com/Follow The State of MedTech onLinkedIn https://www.linkedin.com/company/thestateofmedtechInstagram https://www.instagram.com/stateofmedtech/TikTok https://www.tiktok.com/@stateofmedtechX https://twitter.com/StateofMedTechFacebook https://www.facebook.com/stateofmedtech/Follow Omar M. Khateeb onLinkedIn https://www.linkedin.com/in/okhateeb/Instagram https://www.instagram.com/omar.m.khateeb/TikTok https://www.tiktok.com/@omarkhateebofficialX https://twitter.com/OmarMKhateebFacebook https://www.facebook.com/OmarMKhateeb/#GutHealth #Microbiome #Biohacking #MedTech #HealthTech
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