Send us a textWe dissect a large US POINTER trial and show how structure turns lifestyle advice into measurable cognitive gains for older adults at risk. The four pillars work, but frequent, high-touch support is the multiplier that boosts results and reduces risk.• Who the 2,111 at-risk participants were and why they matter• The four pillars: exercise, MIND diet, cognitive and social engagement, health monitoring• Structured versus self-guided delivery and what changed• Composite Z-scores as the global cognition outcome• Effect size differences and what they mean functionally• Benefits across APOE status, sex, and cardiovascular risk• Safety findings favoring high-touch support• Practical weekly targets for exercise and diet• Why accountability and peer teams increase adherence• Limitations, surrogate outcomes, and future endpointsThis podcast is created by Ai for educational and entertainment purposes only and does not constitute professional medical or health advice. Please talk to your healthcare team for medical advice. Never miss an episode—subscribe on your favorite podcast app!

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