Listen "The Secret to Better Medications: Standardizing Pharmacogenomics (PGx) Testing"
Episode Synopsis
Imagine knowing how your body will respond to a medication before you even take it! In this episode, Harsh Thakkar interviews Sarah Rogers, co-founder and president of the American Society of Pharmacovigilance (ASP) and an Assistant Professor at Texas A&M. Together, they dive deep into the fascinating world of pharmacogenomics—how your genetic makeup affects your response to medications. They discuss the challenges of pharmacogenomic testing, real-world examples of adverse drug reactions, and the future of personalized medicine. Chapters:00:00 - Intro00:16 - Breaking Down Pharmacogenomics01:39 - Guest Introduction: Sarah Rogers 02:18 - Explaining Pharmacogenomics to a Child03:24 - Sarah's Start in Pharmacogenomics 04:54 - The Power of Pharmacogenomics07:00 - Pharmacogenomics Clinic at Texas A&M 09:02 - Challenges of Standardizing PGX Testing11:14 - The Ideal Pharmacogenomics Workflow13:39 - Real-World Example of PGX in Action15:44 - Importance of Integrating PGX into EHR 20:24 - AI and Digital Twins in Pharmacogenomics21:52 - Lessons Learned in Pharmacogenomics24:46 - Looking to the Future of Personalized Medicine28:18 - Final Takeaway 30:22 - Outro Connect with Sarah Rogers:- LinkedIn: (https://www.linkedin.com/company/american-society-of-pharmacovigilance) - STRIPE Initiative LinkedIn: (https://www.linkedin.com/company/stripe-pharmacogenomics) - Twitter: (https://twitter.com/amsocietypharm) - Newsletter signup for the American Society of Pharmacovigilance: https://www.stopadr.org/Here are links for some of the information that I mentioned during our meeting:- STRIPE Annual Meeting and Consensus Workshop - (https://www.usp.org/node/289416) - Collaborative Communities: Addressing Health Care Challenges Together(https://www.fda.gov/about-fda/cdrh-strategic-priorities-and-updates/collaborative-communities-addressing-health-care-challenges-together)- Standardizing Laboratory Practices in Pharmacogenomics (STRIPE) Collaborative Community - (https://stopadr.org/stripe)- Texas A&M Interprofessional Pharmacogenomics (IPGx) Clinic - (https://ibt.tamu.edu/cores/Texas%20ClinicoGenomics/Texas%20ClinicoGenomics.html)- National Action Plan for Adverse Drug Event Prevention - (https://health.gov/sites/default/files/2019-09/ADE-Action-Plan-508c.pdf)- Figure showing Stakeholders Involved in the Lifecycle of a Pharmacogenomics Test(https://www.nature.com/articles/s41397-024-00345-y/figures/1)- Subscribe to our podcast for more insights on life sciences: 🍎Apple podcast: https://apple.co/3RXPoS1🟩 Spotify podcast: https://spoti.fi/3EbDZbr💬 Let us know in the comments: Did you know worms could be this powerful? 👍 Don't forget to hit Like and Subscribe for more fascinating interviews with leaders in life sciences!--- #Pharmacogenomics #PersonalizedMedicine #SarahRogers #PGX #GeneticMakeupFor transcripts, check out the podcast website - www.lifesciencespod.com
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