Episode 27 | Rethinking Rodent Health Panels: Data-Driven Monitoring for Modern Labs

08/07/2025 25 min Episodio 27
Episode 27 | Rethinking Rodent Health Panels: Data-Driven Monitoring for Modern Labs

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Episode Synopsis

What if your health monitoring program could be more effective and more efficient? In this episode of The LASt Word, Dr. Wai H. Hanson, DVM, PhD, DACLAM, joins us to unpack her recently accepted JAALAS paper, 'Guidance on Establishing Health Monitoring Panels for Laboratory Mice to Reflect Contemporary Pathogen Prevalence'. Dr. Hanson shares how her entry into the field coincided with the rise of environmental monitoring, sparking her interest in reevaluating outdated sentinel animal models. She discusses the importance of using current prevalence data to tailor health monitoring panels, streamline testing, and save costs without compromising biosecurity, especially during quarantine. Tune in to explore the paper's practical, consensus-based starting points for institutions to reassess which pathogens to test for, and why. This episode is a must-listen for professionals rethinking lab animal health programs in today's resource-conscious environment!   Key Points From This Episode: Dr. Hanson's path from PhD to lab animal medicine. The emotional impact of moving away from sentinel animals. Meet the team behind the review paper. Role of The 3Rs Collaborative Rodent Health Monitoring Initiative. Insight into why this guidance paper was needed now. Defining key terms: exclusion versus testing lists. How this paper helps new grads and under-resourced institutions. Using commercial prevalence data to rethink and streamline panels. Breaking down tables one and two: core and scenario-specific agents. Rationalizing differences in institutional approaches. Debating the "kitchen sink" approach for immunocompromised mice. Fear versus data in testing decisions: the human element of streamlining panels. Applying the methodology to rats and other species. What inspired this paper's focus on pathogens over methodology.   Links Mentioned in Today's Episode: Dr. Wai H. Hanson 'Guidance on Establishing Health Monitoring Panels for Laboratory Mice to Reflect Contemporary Pathogen Prevalence' The 3Rs Collaborative Rodent Health Monitoring Initiative AALAS Learning Library American Association for Laboratory Animal Science (AALAS) Journal of the American Association for Laboratory Animal Science (JAALAS)The LASt Word: An AALAS Podcast

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