Episode 25 | Extended-Release Buprenorphine in Surgery: A Marmoset Pain-Management Study with Dr. Kasra Pouriani and Dr. Niora Fabian

03/06/2025 41 min Episodio 25
Episode 25 | Extended-Release Buprenorphine in Surgery: A Marmoset Pain-Management Study with Dr. Kasra Pouriani and Dr. Niora Fabian

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Episode Synopsis

Effective pain management in research animals is both an ethical imperative and a scientific necessity. In this episode, we're joined by Dr. Kasra Pouriani and Dr. Niora Fabian from MIT's Division of Comparative Medicine to discuss their recent research comparing extended-release buprenorphine formulations for perioperative pain management in common marmosets. Together, they walk us through their study team, hypothesis, design, and key findings. They also reflect on the challenges they faced and share expert advice for anyone building or refining analgesia protocols in marmoset models. This episode is not one you want to miss so be sure to press play now!   Key Points From This Episode: Introducing today's guests, Dr. Kasra Pouriani and Dr. Niora Fabian. A brief overview of our guests' careers and what led them to this study. Niora tell us about her and Kasra's team for this research study. Kasra shares their hypothesis and our guests discuss the study design. Our guests walk us through some of the results of their study. The limitations and obstacles they faced during this study. Advice for anyone wanting to establish an effective analgesia program for marmosets.   Links Mentioned in Today's Episode: Kasra Pouriani on LinkedIn Niora Fabian on LinkedIn 'Comparison of Different Formulations of Extended-Release Buprenorphine in Perioperative Pain Management in Common Marmosets'American Association for Laboratory Animal Science (AALAS) Journal of the American Association for Laboratory Animal Science (JAALAS)The LASt Word: An AALAS Podcast

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