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Listen "C.M.R. Improves I.C.D. Decisions in Sarcoidosis 09/22/25"
Episode Synopsis
Welcome to Cardiology Today – Recorded September 22, 2025. This episode summarizes 5 key cardiology studies on topics like ventricular tachycardia and atrial fibrillation. Key takeaway: C.M.R. Improves I.C.D. Decisions in Sarcoidosis.
Article Links:
Article 1: Mitral valve replacement or repair and long-term risk of infective endocarditis: a Danish nationwide study. (European heart journal)
Article 2: Prediction of ventricular arrhythmic outcomes in suspected cardiac sarcoidosis: a comparison of cardiovascular magnetic resonance phenotyping vs. societal recommendations for implantable cardioverter-defibrillator placement. (European heart journal)
Article 3: Impact of alternative efficacy endpoint definitions on reported outcomes after ablation of paroxysmal atrial fibrillation – insights from the COMPARE-CRYO study using continuous rhythm monitoring. (Heart rhythm)
Article 4: Ventricular Tachycardia Substrate Mapping with Cardiac Computed Tomography and Cardiac Magnetic Resonance Imaging: Head-to-head Comparison of Two Clinically Available Post-processing Platforms. (Heart rhythm)
Article 5: Outcome of Functional Mitral Regurgitation Associated with Heart Failure with Mildly Reduced or Preserved Ejection Fraction. (The American journal of cardiology)
Full episode page: https://podcast.explainheart.com/podcast/c-m-r-improves-i-c-d-decisions-in-sarcoidosis-09-22-25/
Featured Articles
Article 1: Mitral valve replacement or repair and long-term risk of infective endocarditis: a Danish nationwide study.
Journal: European heart journal
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40641372
Summary: This Danish registry study assessed the 10-year risk of first-time infective endocarditis following mitral valve replacement or repair compared to patients at moderate risk. Results showed that mitral valve replacement carried a significantly higher risk of infective endocarditis than mitral valve repair over the long term. This data underscores the importance of considering infective endocarditis risk when choosing between mitral valve replacement and repair.
Article 2: Prediction of ventricular arrhythmic outcomes in suspected cardiac sarcoidosis: a comparison of cardiovascular magnetic resonance phenotyping vs. societal recommendations for implantable cardioverter-defibrillator placement.
Journal: European heart journal
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40400457
Summary: societal recommendations for implantable cardioverter-defibrillator placement. This study compared cardiovascular magnetic resonance imaging phenotyping to societal guidelines for predicting ventricular arrhythmias in patients with suspected cardiac sarcoidosis, aiming to improve implantable cardioverter defibrillator placement. The findings suggest that cardiovascular magnetic resonance imaging phenotyping may offer superior accuracy in predicting long-term ventricular arrhythmic events compared to guideline-based recommendations. This may lead to more informed decisions regarding implantable cardioverter defibrillator implantation in this complex patient population.
Article 3: Impact of alternative efficacy endpoint definitions on reported outcomes after ablation of paroxysmal atrial fibrillation – insights from the COMPARE-CRYO study using continuous rhythm monitoring.
Journal: Heart rhythm
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40976542
Summary: This sub-analysis of the COMPARE-CRYO study examined how different endpoint definitions impact the assessment of atrial fibrillation ablation success, utilizing continuous rhythm monitoring data from implantable cardiac monitors. The study demonstrated that varying the endpoint definitions based on atrial fibrillation burden, duration, or episode frequency significantly alters the reported success rates post ablation. These findings highlight the importance of standardized endpoint definitions for atrial fibrillation ablation studies and their impact on healthcare utilization.
Article 4: Ventricular Tachycardia Substrate Mapping with Cardiac Computed Tomography and Cardiac Magnetic Resonance Imaging: Head-to-head Comparison of Two Clinically Available Post-processing Platforms.
Journal: Heart rhythm
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40976541
Summary: This study provides a head-to-head comparison of two post-processing platforms, ADAS 3D L.V. and inHEART, for ventricular tachycardia substrate mapping using cardiac computed tomography and late-gadolinium enhanced cardiac magnetic resonance imaging in patients undergoing ventricular tachycardia ablation. The research compared substrate models derived from both modalities using both platforms. The study aims to optimize ventricular tachycardia ablation guidance using cardiac imaging.
Article 5: Outcome of Functional Mitral Regurgitation Associated with Heart Failure with Mildly Reduced or Preserved Ejection Fraction.
Journal: The American journal of cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40976391
Summary: This study investigated the mechanisms and clinical significance of functional mitral regurgitation in patients with heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction. The study found that functional mitral regurgitation has a significant impact on long-term outcomes in both heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction. Identifying the predominant mechanisms of functional mitral regurgitation in each group is crucial for tailored management strategies.
Transcript
Today’s date is September 22, 2025. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Mitral valve replacement or repair and long-term risk of infective endocarditis: a Danish nationwide study. This Danish registry study assessed the 10-year risk of first-time infective endocarditis following mitral valve replacement or repair compared to patients at moderate risk. Results showed that mitral valve replacement carried a significantly higher risk of infective endocarditis than mitral valve repair over the long term. This data underscores the importance of considering infective endocarditis risk when choosing between mitral valve replacement and repair.
Article number two. Prediction of ventricular arrhythmic outcomes in suspected cardiac sarcoidosis: a comparison of cardiovascular magnetic resonance phenotyping vs. societal recommendations for implantable cardioverter-defibrillator placement. This study compared cardiovascular magnetic resonance imaging phenotyping to societal guidelines for predicting ventricular arrhythmias in patients with suspected cardiac sarcoidosis, aiming to improve implantable cardioverter defibrillator placement. The findings suggest that cardiovascular magnetic resonance imaging phenotyping may offer superior accuracy in predicting long-term ventricular arrhythmic events compared to guideline-based recommendations. This may lead to more informed decisions regarding implantable cardioverter defibrillator implantation in this complex patient population.
Article number three. Impact of alternative efficacy endpoint definitions on reported outcomes after ablation of paroxysmal atrial fibrillation – insights from the COMPARE-CRYO study using continuous rhythm monitoring. This sub-analysis of the COMPARE-CRYO study examined how different endpoint definitions impact the assessment of atrial fibrillation ablation success, utilizing continuous rhythm monitoring data from implantable cardiac monitors. The study demonstrated that varying the endpoint definitions based on atrial fibrillation burden, duration, or episode frequency significantly alters the reported success rates post ablation. These findings highlight the importance of standardized endpoint definitions for atrial fibrillation ablation studies and their impact on healthcare utilization.
Article number four. Ventricular Tachycardia Substrate Mapping with Cardiac Computed Tomography and Cardiac Magnetic Resonance Imaging: Head-to-head Comparison of Two Clinically Available Post-processing Platforms. This study provides a head-to-head comparison of two post-processing platforms, ADAS 3D L.V. and inHEART, for ventricular tachycardia substrate mapping using cardiac computed tomography and late-gadolinium enhanced cardiac magnetic resonance imaging in patients undergoing ventricular tachycardia ablation. The research compared substrate models derived from both modalities using both platforms. The study aims to optimize ventricular tachycardia ablation guidance using cardiac imaging.
Article number five. Outcome of Functional Mitral Regurgitation Associated with Heart Failure with Mildly Reduced or Preserved Ejection Fraction. This study investigated the mechanisms and clinical significance of functional mitral regurgitation in patients with heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction. The study found that functional mitral regurgitation has a significant impact on long-term outcomes in both heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction. Identifying the predominant mechanisms of functional mitral regurgitation in each group is crucial for tailored management strategies.
Thank you for listening. Don’t forget to subscribe.
Keywords
ventricular tachycardia, atrial fibrillation, functional mitral regurgitation, arrhythmia burden, implantable cardioverter defibrillator, implantable cardiac monitor, substrate mapping, ablation, Heart Failure with Preserved Ejection Fraction, cardiac magnetic resonance imaging, endpoint definition, heart failure with mildly reduced ejection fraction, cardiac computed tomography, ablation guidance, cardiovascular magnetic resonance imaging, cardiac sarcoidosis, prognosis, mechanisms, mitral valve, long-term risk, risk prediction, infective endocarditis, valve repair, valve replacement, ventricular arrhythmia.
About
Concise summaries of cardiovascular research for professionals.
Subscribe • Share • FollowThe post C.M.R. Improves I.C.D. Decisions in Sarcoidosis 09/22/25 first appeared on Cardiology Today.
Article Links:
Article 1: Mitral valve replacement or repair and long-term risk of infective endocarditis: a Danish nationwide study. (European heart journal)
Article 2: Prediction of ventricular arrhythmic outcomes in suspected cardiac sarcoidosis: a comparison of cardiovascular magnetic resonance phenotyping vs. societal recommendations for implantable cardioverter-defibrillator placement. (European heart journal)
Article 3: Impact of alternative efficacy endpoint definitions on reported outcomes after ablation of paroxysmal atrial fibrillation – insights from the COMPARE-CRYO study using continuous rhythm monitoring. (Heart rhythm)
Article 4: Ventricular Tachycardia Substrate Mapping with Cardiac Computed Tomography and Cardiac Magnetic Resonance Imaging: Head-to-head Comparison of Two Clinically Available Post-processing Platforms. (Heart rhythm)
Article 5: Outcome of Functional Mitral Regurgitation Associated with Heart Failure with Mildly Reduced or Preserved Ejection Fraction. (The American journal of cardiology)
Full episode page: https://podcast.explainheart.com/podcast/c-m-r-improves-i-c-d-decisions-in-sarcoidosis-09-22-25/
Featured Articles
Article 1: Mitral valve replacement or repair and long-term risk of infective endocarditis: a Danish nationwide study.
Journal: European heart journal
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40641372
Summary: This Danish registry study assessed the 10-year risk of first-time infective endocarditis following mitral valve replacement or repair compared to patients at moderate risk. Results showed that mitral valve replacement carried a significantly higher risk of infective endocarditis than mitral valve repair over the long term. This data underscores the importance of considering infective endocarditis risk when choosing between mitral valve replacement and repair.
Article 2: Prediction of ventricular arrhythmic outcomes in suspected cardiac sarcoidosis: a comparison of cardiovascular magnetic resonance phenotyping vs. societal recommendations for implantable cardioverter-defibrillator placement.
Journal: European heart journal
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40400457
Summary: societal recommendations for implantable cardioverter-defibrillator placement. This study compared cardiovascular magnetic resonance imaging phenotyping to societal guidelines for predicting ventricular arrhythmias in patients with suspected cardiac sarcoidosis, aiming to improve implantable cardioverter defibrillator placement. The findings suggest that cardiovascular magnetic resonance imaging phenotyping may offer superior accuracy in predicting long-term ventricular arrhythmic events compared to guideline-based recommendations. This may lead to more informed decisions regarding implantable cardioverter defibrillator implantation in this complex patient population.
Article 3: Impact of alternative efficacy endpoint definitions on reported outcomes after ablation of paroxysmal atrial fibrillation – insights from the COMPARE-CRYO study using continuous rhythm monitoring.
Journal: Heart rhythm
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40976542
Summary: This sub-analysis of the COMPARE-CRYO study examined how different endpoint definitions impact the assessment of atrial fibrillation ablation success, utilizing continuous rhythm monitoring data from implantable cardiac monitors. The study demonstrated that varying the endpoint definitions based on atrial fibrillation burden, duration, or episode frequency significantly alters the reported success rates post ablation. These findings highlight the importance of standardized endpoint definitions for atrial fibrillation ablation studies and their impact on healthcare utilization.
Article 4: Ventricular Tachycardia Substrate Mapping with Cardiac Computed Tomography and Cardiac Magnetic Resonance Imaging: Head-to-head Comparison of Two Clinically Available Post-processing Platforms.
Journal: Heart rhythm
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40976541
Summary: This study provides a head-to-head comparison of two post-processing platforms, ADAS 3D L.V. and inHEART, for ventricular tachycardia substrate mapping using cardiac computed tomography and late-gadolinium enhanced cardiac magnetic resonance imaging in patients undergoing ventricular tachycardia ablation. The research compared substrate models derived from both modalities using both platforms. The study aims to optimize ventricular tachycardia ablation guidance using cardiac imaging.
Article 5: Outcome of Functional Mitral Regurgitation Associated with Heart Failure with Mildly Reduced or Preserved Ejection Fraction.
Journal: The American journal of cardiology
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40976391
Summary: This study investigated the mechanisms and clinical significance of functional mitral regurgitation in patients with heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction. The study found that functional mitral regurgitation has a significant impact on long-term outcomes in both heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction. Identifying the predominant mechanisms of functional mitral regurgitation in each group is crucial for tailored management strategies.
Transcript
Today’s date is September 22, 2025. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Mitral valve replacement or repair and long-term risk of infective endocarditis: a Danish nationwide study. This Danish registry study assessed the 10-year risk of first-time infective endocarditis following mitral valve replacement or repair compared to patients at moderate risk. Results showed that mitral valve replacement carried a significantly higher risk of infective endocarditis than mitral valve repair over the long term. This data underscores the importance of considering infective endocarditis risk when choosing between mitral valve replacement and repair.
Article number two. Prediction of ventricular arrhythmic outcomes in suspected cardiac sarcoidosis: a comparison of cardiovascular magnetic resonance phenotyping vs. societal recommendations for implantable cardioverter-defibrillator placement. This study compared cardiovascular magnetic resonance imaging phenotyping to societal guidelines for predicting ventricular arrhythmias in patients with suspected cardiac sarcoidosis, aiming to improve implantable cardioverter defibrillator placement. The findings suggest that cardiovascular magnetic resonance imaging phenotyping may offer superior accuracy in predicting long-term ventricular arrhythmic events compared to guideline-based recommendations. This may lead to more informed decisions regarding implantable cardioverter defibrillator implantation in this complex patient population.
Article number three. Impact of alternative efficacy endpoint definitions on reported outcomes after ablation of paroxysmal atrial fibrillation – insights from the COMPARE-CRYO study using continuous rhythm monitoring. This sub-analysis of the COMPARE-CRYO study examined how different endpoint definitions impact the assessment of atrial fibrillation ablation success, utilizing continuous rhythm monitoring data from implantable cardiac monitors. The study demonstrated that varying the endpoint definitions based on atrial fibrillation burden, duration, or episode frequency significantly alters the reported success rates post ablation. These findings highlight the importance of standardized endpoint definitions for atrial fibrillation ablation studies and their impact on healthcare utilization.
Article number four. Ventricular Tachycardia Substrate Mapping with Cardiac Computed Tomography and Cardiac Magnetic Resonance Imaging: Head-to-head Comparison of Two Clinically Available Post-processing Platforms. This study provides a head-to-head comparison of two post-processing platforms, ADAS 3D L.V. and inHEART, for ventricular tachycardia substrate mapping using cardiac computed tomography and late-gadolinium enhanced cardiac magnetic resonance imaging in patients undergoing ventricular tachycardia ablation. The research compared substrate models derived from both modalities using both platforms. The study aims to optimize ventricular tachycardia ablation guidance using cardiac imaging.
Article number five. Outcome of Functional Mitral Regurgitation Associated with Heart Failure with Mildly Reduced or Preserved Ejection Fraction. This study investigated the mechanisms and clinical significance of functional mitral regurgitation in patients with heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction. The study found that functional mitral regurgitation has a significant impact on long-term outcomes in both heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction. Identifying the predominant mechanisms of functional mitral regurgitation in each group is crucial for tailored management strategies.
Thank you for listening. Don’t forget to subscribe.
Keywords
ventricular tachycardia, atrial fibrillation, functional mitral regurgitation, arrhythmia burden, implantable cardioverter defibrillator, implantable cardiac monitor, substrate mapping, ablation, Heart Failure with Preserved Ejection Fraction, cardiac magnetic resonance imaging, endpoint definition, heart failure with mildly reduced ejection fraction, cardiac computed tomography, ablation guidance, cardiovascular magnetic resonance imaging, cardiac sarcoidosis, prognosis, mechanisms, mitral valve, long-term risk, risk prediction, infective endocarditis, valve repair, valve replacement, ventricular arrhythmia.
About
Concise summaries of cardiovascular research for professionals.
Subscribe • Share • FollowThe post C.M.R. Improves I.C.D. Decisions in Sarcoidosis 09/22/25 first appeared on Cardiology Today.
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