Send us a text🧪 The EPOC Trial:Compared FLOT chemotherapy alone vs chemo + radiation before surgery in localized esophageal/gastroesophageal adenocarcinoma.📈 Findings:FLOT alone led to better 3-year progression-free survival: 51.6% vs 35%.No survival benefit from adding radiation.Patients receiving FLOT alone had fewer complications, improved tolerance, and less treatment-related morbidity.🧩 Clinical Takeaway:For operable esophageal adenocarcinoma, skip the radiation if you're doing full-dose chemo.Less burden for patients, especially elderly or frail.

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