Is NAD+ a miracle anti-ageing supplement?

06/11/2024 18 min
Is NAD+ a miracle anti-ageing supplement?

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Episode Synopsis


We've been searching for a fountain of youth for millennia. How can we not only live longer, but live healthier for longer?Nicotinamide adenine dinucleotide (NAD) is the latest anti-ageing candidate under the microscope.Norman and Tegan explain what it is, and whether supplements promising to boost NAD actually do what's advertised on the bottle.References:NAD+ metabolism and its roles in cellular processes during ageingNAD+ in Brain Aging and Neurodegenerative DisordersWhat is really known about the effects of nicotinamide riboside supplementation in humansDietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future DirectionsThe use of a systems approach to increase NAD+ in human participantsSpecific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging