S1E4 - TBD on CBD?: A placebo-controlled RCT of CBD in COVID-19

05/06/2023 40 min Temporada 1 Episodio 4
S1E4 - TBD on CBD?: A placebo-controlled RCT of CBD in COVID-19

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Episode Synopsis

Welcome to What's it Worth! Join your hosts, Dr. Diana Langworthy, Nathan Uk, and Garrison Griest as we take on the evidence behind a trending treatment for COVID-19.  Our guest, Dr. Ann Philbrick, PharmD, BCACP, will share her expertise with medical cannabis products to help figure out what is TBD about CBD in COVID-19.     Key Points Cannabidiol (CBD) has some purported anti-inflammatory properties from in-vitro studies and was investigated to prevent progression of COVID-19 to moderate or severe disease Pharmacists can use their EBP skills to serve as information experts to prevent progression of information to misinformation! Recognizing statistical tests (i.e. Student's T Test and Chi Square Test) and the data they are used to analyze is a core skills of evidence analysis Cannabidiol doses used in this investigation were much higher than typical CBD doses in OTC products Peanutbutter has evidence for use in a scientific smell test -> TUNE IN to find out more about the science behind the peanutbutter smell test! References [EPISODE TRIAL] Crippa JAS, Pacheco JC, Zuardi AW, et al.  Cannabidiol for COVID-19 Patients with Mild to Moderate Symptoms (CANDIDATE Study): A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.  Cannabis and Cannabinoid Research 2022;7(5):658-669. Stamps JJ, Bartoshuk LM, Heilman KM.  A brief olfactory test for Alzheimer's disease.  Journal of the Neurological Sciences 2013;333(1-2):19-24. [NOTE: this peanutbutter smell test results have not been successfully replicated in other studies so it's true utility is not clear] DiCenzo, Robert. "Choosing the Appropriate Statistical Test." Clinical Pharmacist's Guide to Biostatistics and Literature Evaluation, American College of Clinical Pharmacy, Lenexa, KS, 2015, pp. 23–37.   Contact Information Podcast email: [email protected] Host Information Dr. Diana R. Langworthy, PharmD, BCPS Clinical Associate Professor, University of Minnesota College of Pharmacy Clinical Pharmacist - Inpatient Internal Medicine, M Health Fairview East Bank Hospital Guest Host Information Garrison Griest, Student Pharmacist, Class of 2025  University of Minnesota Nathan Uk, Student Pharmacist, Class of 2025  University of Minnesota Guest Expert Dr. Ann Philbrick, PharmD, BCACP, Associate Professor, University of Minnesota College of Pharmacy

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