Today’s guest is Ayele Argaw-Denboba from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany, and one of the 2025 Prize Winners of the NOSTER & Science Microbiome Prize. is essay, “The gut microbiome–germline axis,” shows that disturbances in a father’s gut microbes can alter sperm and pass on health risks to the next generation — but restoring the microbiome can reverse these effects.Ayele Argaw-DenbobaThe gut microbiome–germline axis: Does a prospective father’s gut microbiota matter?Science 389,38-38 (2025).DOI:10.1126/science.adz0492

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