Use of diabetes medications in non-approved (aka off-label) ways is increasingly common. This month, Amy and Liz dig into common off-label usage of Type 2 medications in insulin-deficient diabetes. Meds like GLP-1s, SLGT2’s, and metformin have an established history as a treatment for improving insulin sensitivity in T1’s. Ever wonder how that works and what the potential down sides are? While they’re on the topic of medications used for non-FDA-approved purposes, stay for the second half of the episode where they delve into use of supplements (cinnamon and turmeric) for diabetes management and if/how it works (the answer may surprise you) (or not).Instagram @diacastpodcast (https://www.instagram.com/diacastpodcast/)Facebook Diacast (https://www.facebook.com/diacastpodcast)Email us at [email protected] feel free to join the wonderful diabetes communities on Reddit and Discord.r/diabetes subreddit:https://www.reddit.com/r/diabetes/r/Diabetes discord:discord.gg/diabetesPatreon (help us stop losing money - plus early access, bloopers, and more!)https://patreon.com/diacastReference Linkshttps://diatribe.org/how-people-diabetes-are-getting-during-ozempic-shortageOff-Label Medication in T1D https://www.utsouthwestern.edu/newsroom/articles/year-2023/february-type-1-diabetes.htmlGLP-1s in T1D https://www.endocrinologyadvisor.com/home/topics/diabetes/type-1-diabetes/type-1-diabetes-adjunct-insulin-therapy-glucagon-like-peptide-1-receptor-agonists-glp-1-ra/Current and Therapeutic Use of Metformin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915435/Metformin in T1D [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771191/#:~:text=Metformin reduces hepatic glucose production,20%2C 21%2C 26]](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771191/#:~:text=Metformin reduces hepatic glucose production,20%2C 21%2C 26])https://www.sciencedirect.com/science/article/pii/S2589936821000049Metformin as an anti-cancer med https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497052/#:~:text=Based on recent analyses and,prostate%2C colon%2C pancreas%2C andTZDs in Diabetic Children and Beta Cell Preservation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890222/TZDs Info https://dtc.ucsf.edu/types-of-diabetes/type2/treatment-of-type-2-diabetes/medications-and-therapies/type-2-non-insulin-therapies/insulin-sensitizers/TZDs in T2 Treatment

Ver todos los episodios