We’ve all heard it: dopamine is the “pleasure molecule.” Catchy, sure. But wrong. In this episode of The Cognitive Performer, Marco Rigazio unpacks the myths around dopamine and explores its real role in the brain. Far from being just about “feeling good,” dopamine is a regulator—shaping focus, working memory, and even intelligence. Along the way, you’ll discover what happens when dopamine falls out of balance (ADHD, addiction, burnout, anhedonia) and why motivation isn’t just about willpower, but about your brain’s state of readiness.Copyright 2026 Marco Rigazio Molecular Imaging of Central Dopamine in Obesity: A Qualitative Review across Substrates and Radiotracers - PMCAge-dependent effects of protein restriction on dopamine release - PMCThe Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects - PubMedThe tonic/phasic model of dopamine system regulation: its relevance for understanding how stimulant abuse can alter basal ganglia function - PubMedThe tonic/phasic model of dopamine system regulation and its implications for understanding alcohol and psychostimulant craving - PubMedDopamine D2/D3 receptor availability and working memory in stimulant use disorderNeurobiology of Schizophrenia: A Comprehensive Review - PMCWhite-Matter Integrity and Working Memory: Links to Aging and Dopamine-Related Genes - PMCA multi-faceted role of dual-state dopamine signaling in working memory, attentional control, and intelligence - PMCDopamine-related polymorphisms and Affective Working Memory in aging - PubMedEffects of Caffeine Consumption on Attention Deficit Hyperactivity Disorder (ADHD) Treatment: A Systematic Review of Animal Studies - PMCAdult Attention-Deficit/Hyperactivity Disorder: a Narrative Review of Biological Mechanisms, Treatments, and Outcomes - PubMedEffects of physical exercise on children with attention deficit hyperactivity disorder - PMCThe Cognitive-Enhancing Outcomes of Caffeine and L-theanine: A Systematic Review - PMCThe Effects of Drugs used for the Treatment of Attention Deficit Hyperactivity Disorder (ADHD) on Pregnancy Outcome and Breast-feeding: A Critical Review - PMCDezocine modulates the reinstatement of conditioned place preference in morphine-dependent rats via the dopamine reward circuitry - PMCFrom Reward to Anhedonia-Dopamine Function in the Global Mental Health Context - PMCReward, motivation and brain imaging in human healthy participants – A narrative review - PMCDopamine synthesis and transport:...

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