Electrolytes - Hypophosphatemia and Hyperphosphatemia

17/08/2025 7 min
Electrolytes - Hypophosphatemia and Hyperphosphatemia

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Episode Synopsis

Phosphorus doesn’t always get the spotlight—but on test day, it’s a game changer. From energy metabolism to bone health, imbalances can wreck patients and trip you up on the shelf.In this episode, Chris and Mars break down the most high-yield phosphorus scenarios you need to master: Refeeding Syndrome, DKA after insulin therapy, Hungry Bone Syndrome, antacid and binder use, Fanconi syndrome, CKD-related hyperphosphatemia, tumor lysis syndrome, and post-thyroidectomy hypoparathyroidism. You’ll learn the classic presentations, the underlying pathophysiology, and the treatment pearls that show up again and again.We cover:Why refeeding syndrome causes a dangerous phosphate crashHow insulin in DKA unmasks total body phosphate depletionThe difference between Hungry Bone Syndrome and surgical hypoparathyroidismKey pitfalls of antacids and phosphate bindersWhat to do when CKD or tumor lysis drives phosphate dangerously highPerfect for med students gearing up for the surgery shelf—this one locks in both the physiology and the test-day clues.