DDIT3 Immunohistochemical expression as a diagnostic marker for Myxoid Liposarcoma

20/08/2021 17 min
DDIT3 Immunohistochemical expression as a diagnostic marker for Myxoid Liposarcoma

Listen "DDIT3 Immunohistochemical expression as a diagnostic marker for Myxoid Liposarcoma"

Episode Synopsis

Dr. Jason Hornick discusses his team recent study finding that a monoclonal antibody directed against the N-terminus of DDIT3 is a highly sensitive and specific for high-grade MLPS. DDIT3 immunostains could replace molecular genetic testing in many cases, although limited labeling may be seen in a range of other tumor types.