Welcome back to Rad Onc Smart Review! This is Episode 39B, the second installment of our special series on Radiobiology Calculations. Today, our focus is on Tumor Control & Kinetics. In our last episode, we mastered the calculations for cell survival on a microscopic level. Now, we're scaling up to the macroscopic world of clinical tumors. We'll start by calculating the massive radiation doses required to eradicate billions of tumor cells, connecting this to the concept of Tumor Control Probability, or TCP. We'll then shift gears to explore the dynamics of tumor growth, learning how to relate a tumor's change in size to its underlying cell doublings and how factors like cell loss influence its growth rate.

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