Biochemistry | Pentose Phosphate Pathway

21/12/2025 14 min Episodio 85
Biochemistry | Pentose Phosphate Pathway

Listen "Biochemistry | Pentose Phosphate Pathway"

Episode Synopsis

🍐 In this episode of PodBites, Amr and Abdulrahman break down the pentose phosphate pathway — glycolysis’s side quest that keeps cells protected, building, and alive under oxidative stress.
🎙️ Tune in to explore:


What the pentose phosphate pathway is and why it matters


The two main products: NADPH and ribose-5-phosphate


Oxidative vs non-oxidative phases and why one is irreversible


G6PD as the rate-limiting enzyme


The role of NADPH in glutathione, oxidative stress, and the respiratory burst


Key clinical ties like G6PD deficiency and hemolytic anemia


How the pathway links back to glycolysis


🌟 A clear, high-yield explanation that turns PPP from a memorization headache into a pathway that actually clicks.