New research links chronic stress, brain energy, and psychiatric conditions, including PTSD, depression, and bipolar disorder.Stress doesn’t just impact your mood; it affects how your brain allocates energy. In this interview, Dr. Bret Scher sits down with Dr. Parker Kelly, a postdoctoral fellow at UCSF and the San Francisco VA, to unpack the Allostatic Triage Model of Psychopathology, a new framework proposing that psychiatric symptoms may emerge when the brain is forced to triage limited metabolic resources under chronic stress. Co-authored with mitochondrial researcher Dr. Martin Picard, this model could shift how we understand and treat mental illness.In this conversation, you’ll learn:How stress drives brain energy dysfunctionWhy mitochondria and metabolism may be central to mental illnessWhich brain networks are impacted by energy deficitsThe role of predictability and routine in stress resilienceHow metabolic therapies like nutrition, sleep, and even psychedelics, may support brain energy regulationThis conversation bridges neuroscience, metabolism, and mental health, offering a unique and unifying lens on complex psychiatric conditions.👉Subscribe to Metabolic Mind for more conversations about metabolic health, metabolic psychiatry, and mental health: https://www.youtube.com/@metabolicmind.#MetabolicMind #KetogenicTherapy #NeuroscienceExpert Featured:D. Parker KelleyX.com/sequencemyneurohttps://bsky.app/profile/sequencemyneuro.bsky.socialhttps://www.linkedin.com/in/dparkerkelleyphd/Resources Mentioned:The allostatic triage model of psychopathology (ATP Model): How reallocation of brain energetic resources under stress elicits psychiatric symptomshttps://doi.org/10.1016/j.neubiorev.2025.106419Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of...

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