Quantifying triglyceride-rich lipoprotein atherogenicity, associations with inflammation, and implications for risk assessment using non-HDL cholesterol

JACC This Week
23/09/2024 10 min
Quantifying triglyceride-rich lipoprotein atherogenicity, associations with inflammation, and implications for risk assessment using non-HDL cholesterol

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Episode Synopsis

In this insightful discussion from the October 1, 2024 issue of JACC, researchers reveal that triglyceride-rich lipoprotein (TRL) remnants are significantly more atherogenic than LDL cholesterol, suggesting a need for updated risk assessment strategies. The study advocates for a shift towards evaluating lipoproteins on a per-particle basis, which could revolutionize the diagnosis and treatment of lipid disorders by focusing on the functional activity of these particles.

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