HD CAREGIVERS, WE NEED YOUR HELP! To prepare for a clinical trial of a drug that may reduce the disruptive aggressive behavior that some persons or patients with HD suffer from, we would like to interview about 25 caregivers who are parents, spouses, or adult children of patients who have aggressive outbursts. We are specifically interested in trying to build a list of words that can be used to describe these physically aggressive, acting out, or other threatening behaviors. The research is sponsored by Azevan Pharmaceuticals, Inc. The interviews will be conducted by Erin Koppel, who works at the Huntington's Disease Society of America Center of Excellence at Georgetown University. We will provide a special cell phone number that guarantees the privacy of the connection. The calls will be voice recorded and transcribed so that they can be reviewed more easily. The information that you provide will be stored in password-protected files at Georgetown University. You must be fluent in English and at least 18 years old to participate. Participants that complete the full interview, which involves answering questions about aggressive outbursts and related behaviors, will be compensated $50 for their time and insight. Thank you very much for considering this request. If you are interested in helping us, please call or email Erin Koppel at: 202-893-1115 [email protected]

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