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Listen "Height Drives Hypertension in Older Women 09/24/25"
Episode Synopsis
Welcome to Cardiology Today – Recorded September 24, 2025. This episode summarizes 5 key cardiology studies on topics like systolic blood pressure and Heart Failure with Preserved Ejection Fraction. Key takeaway: Height Drives Hypertension in Older Women.
Article Links:
Article 1: Height May Explain Sex Differences in Systolic Blood Pressure in Older Adults. (Hypertension (Dallas, Tex. : 1979))
Article 2: Long-Term Impact of Platelet Reactivity and Clinical Risk on Clinical Outcomes in Patients With Coronary Artery Disease: Analysis of the PTRG-DES Registry. (Circulation. Cardiovascular interventions)
Article 3: Transpulmonary Proteome Gradients Identify Pathways Involved in Pulmonary Vascular Disease Due To Heart Failure. (Circulation. Heart failure)
Article 4: Nationwide implementation of heart failure therapies: National Heart Failure Center Accreditation Program (HF-CAP) in China. (European journal of heart failure)
Article 5: Dynamic tricuspid regurgitation in heart failure with preserved ejection fraction. (European journal of heart failure)
Full episode page: https://podcast.explainheart.com/podcast/height-drives-hypertension-in-older-women-09-24-25/
Featured Articles
Article 1: Height May Explain Sex Differences in Systolic Blood Pressure in Older Adults.
Journal: Hypertension (Dallas, Tex. : 1979)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40977399
Summary: This study analyzed data from the National Health and Nutrition Examination Surveys, examining older women and men with hypertension. The analysis suggests that differences in height contribute to higher systolic blood pressure values in older women compared to men, potentially explaining lower hypertension control rates in women. These findings highlight the importance of considering height when managing hypertension in older adults, especially in women.
Article 2: Long-Term Impact of Platelet Reactivity and Clinical Risk on Clinical Outcomes in Patients With Coronary Artery Disease: Analysis of the PTRG-DES Registry.
Journal: Circulation. Cardiovascular interventions
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40977391
Summary: Registry. This study from the P.T.R.G.-D.E.S. registry assessed the interaction between platelet reactivity and clinical risk, as determined by the Thrombolysis in Myocardial Infarction Risk Score for Secondary Prevention, on clinical outcomes after percutaneous coronary intervention. The results showed that high platelet reactivity, combined with high clinical risk scores, was associated with increased adverse clinical events in patients with coronary artery disease treated with drug-eluting stents. This suggests that tailoring antiplatelet therapy based on both platelet function and clinical risk assessment could improve outcomes after percutaneous coronary intervention.
Article 3: Transpulmonary Proteome Gradients Identify Pathways Involved in Pulmonary Vascular Disease Due To Heart Failure.
Journal: Circulation. Heart failure
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40985143
Summary: This study investigated transpulmonary protein gradients in patients with Heart Failure with Reduced Ejection Fraction to identify mediators of pulmonary vascular disease. Proteomic analysis revealed distinct protein signatures associated with pulmonary vascular disease development in the setting of heart failure. The identified pathways may represent potential therapeutic targets for preventing or treating pulmonary vascular disease in patients with heart failure.
Article 4: Nationwide implementation of heart failure therapies: National Heart Failure Center Accreditation Program (HF-CAP) in China.
Journal: European journal of heart failure
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40982271
Summary: This study evaluated the impact of the National Heart Failure Center Accreditation Program in China on heart failure therapy implementation. Results indicated that hospitals participating in the accreditation program demonstrated improved adherence to guideline-directed medical therapy for heart failure patients. The nationwide implementation of standardized heart failure care through accreditation programs can lead to better treatment and outcomes.
Article 5: Dynamic tricuspid regurgitation in heart failure with preserved ejection fraction.
Journal: European journal of heart failure
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40977275
Summary: This study investigated the changes in tricuspid regurgitation severity during exercise in patients with Heart Failure with Preserved Ejection Fraction using invasive hemodynamic exercise testing and echocardiography. The study found that tricuspid regurgitation often worsens during exercise in these patients, correlating with hemodynamic changes, reduced cardiopulmonary reserve, and worse prognosis. These findings highlight the importance of assessing dynamic tricuspid regurgitation during exercise in Heart Failure with Preserved Ejection Fraction for risk stratification and management.
Transcript
Today’s date is September 24, 2025. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Height May Explain Sex Differences in Systolic Blood Pressure in Older Adults. This study analyzed data from the National Health and Nutrition Examination Surveys, examining older women and men with hypertension. The analysis suggests that differences in height contribute to higher systolic blood pressure values in older women compared to men, potentially explaining lower hypertension control rates in women. These findings highlight the importance of considering height when managing hypertension in older adults, especially in women.
Article number two. Long-Term Impact of Platelet Reactivity and Clinical Risk on Clinical Outcomes in Patients With Coronary Artery Disease: Analysis of the P.T.R.G.-D.E.S. Registry. This study from the P.T.R.G.-D.E.S. registry assessed the interaction between platelet reactivity and clinical risk, as determined by the Thrombolysis in Myocardial Infarction Risk Score for Secondary Prevention, on clinical outcomes after percutaneous coronary intervention. The results showed that high platelet reactivity, combined with high clinical risk scores, was associated with increased adverse clinical events in patients with coronary artery disease treated with drug-eluting stents. This suggests that tailoring antiplatelet therapy based on both platelet function and clinical risk assessment could improve outcomes after percutaneous coronary intervention.
Article number three. Transpulmonary Proteome Gradients Identify Pathways Involved in Pulmonary Vascular Disease Due To Heart Failure. This study investigated transpulmonary protein gradients in patients with Heart Failure with Reduced Ejection Fraction to identify mediators of pulmonary vascular disease. Proteomic analysis revealed distinct protein signatures associated with pulmonary vascular disease development in the setting of heart failure. The identified pathways may represent potential therapeutic targets for preventing or treating pulmonary vascular disease in patients with heart failure.
Article number four. Nationwide implementation of heart failure therapies: National Heart Failure Center Accreditation Program (H.F.-C.A.P.) in China. This study evaluated the impact of the National Heart Failure Center Accreditation Program in China on heart failure therapy implementation. Results indicated that hospitals participating in the accreditation program demonstrated improved adherence to guideline-directed medical therapy for heart failure patients. The nationwide implementation of standardized heart failure care through accreditation programs can lead to better treatment and outcomes.
Article number five. Dynamic tricuspid regurgitation in heart failure with preserved ejection fraction. This study investigated the changes in tricuspid regurgitation severity during exercise in patients with Heart Failure with Preserved Ejection Fraction using invasive hemodynamic exercise testing and echocardiography. The study found that tricuspid regurgitation often worsens during exercise in these patients, correlating with hemodynamic changes, reduced cardiopulmonary reserve, and worse prognosis. These findings highlight the importance of assessing dynamic tricuspid regurgitation during exercise in Heart Failure with Preserved Ejection Fraction for risk stratification and management.
Thank you for listening. Don’t forget to subscribe.
Keywords
systolic blood pressure, Heart Failure with Preserved Ejection Fraction, H.F.-C.A.P., height, heart failure, proteomics, accreditation program, pulmonary hypertension, hypertension, China, pulmonary vascular disease, hemodynamics, older adults, guideline-directed medical therapy, coronary artery disease, tricuspid regurgitation, exercise, Thrombolysis in Myocardial Infarction Risk Score for Secondary Prevention, Heart Failure with Reduced Ejection Fraction, platelet reactivity, percutaneous coronary intervention, drug-eluting stents, transpulmonary gradient, sex differences.
About
Concise summaries of cardiovascular research for professionals.
Subscribe • Share • FollowThe post Height Drives Hypertension in Older Women 09/24/25 first appeared on Cardiology Today.
Article Links:
Article 1: Height May Explain Sex Differences in Systolic Blood Pressure in Older Adults. (Hypertension (Dallas, Tex. : 1979))
Article 2: Long-Term Impact of Platelet Reactivity and Clinical Risk on Clinical Outcomes in Patients With Coronary Artery Disease: Analysis of the PTRG-DES Registry. (Circulation. Cardiovascular interventions)
Article 3: Transpulmonary Proteome Gradients Identify Pathways Involved in Pulmonary Vascular Disease Due To Heart Failure. (Circulation. Heart failure)
Article 4: Nationwide implementation of heart failure therapies: National Heart Failure Center Accreditation Program (HF-CAP) in China. (European journal of heart failure)
Article 5: Dynamic tricuspid regurgitation in heart failure with preserved ejection fraction. (European journal of heart failure)
Full episode page: https://podcast.explainheart.com/podcast/height-drives-hypertension-in-older-women-09-24-25/
Featured Articles
Article 1: Height May Explain Sex Differences in Systolic Blood Pressure in Older Adults.
Journal: Hypertension (Dallas, Tex. : 1979)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40977399
Summary: This study analyzed data from the National Health and Nutrition Examination Surveys, examining older women and men with hypertension. The analysis suggests that differences in height contribute to higher systolic blood pressure values in older women compared to men, potentially explaining lower hypertension control rates in women. These findings highlight the importance of considering height when managing hypertension in older adults, especially in women.
Article 2: Long-Term Impact of Platelet Reactivity and Clinical Risk on Clinical Outcomes in Patients With Coronary Artery Disease: Analysis of the PTRG-DES Registry.
Journal: Circulation. Cardiovascular interventions
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40977391
Summary: Registry. This study from the P.T.R.G.-D.E.S. registry assessed the interaction between platelet reactivity and clinical risk, as determined by the Thrombolysis in Myocardial Infarction Risk Score for Secondary Prevention, on clinical outcomes after percutaneous coronary intervention. The results showed that high platelet reactivity, combined with high clinical risk scores, was associated with increased adverse clinical events in patients with coronary artery disease treated with drug-eluting stents. This suggests that tailoring antiplatelet therapy based on both platelet function and clinical risk assessment could improve outcomes after percutaneous coronary intervention.
Article 3: Transpulmonary Proteome Gradients Identify Pathways Involved in Pulmonary Vascular Disease Due To Heart Failure.
Journal: Circulation. Heart failure
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40985143
Summary: This study investigated transpulmonary protein gradients in patients with Heart Failure with Reduced Ejection Fraction to identify mediators of pulmonary vascular disease. Proteomic analysis revealed distinct protein signatures associated with pulmonary vascular disease development in the setting of heart failure. The identified pathways may represent potential therapeutic targets for preventing or treating pulmonary vascular disease in patients with heart failure.
Article 4: Nationwide implementation of heart failure therapies: National Heart Failure Center Accreditation Program (HF-CAP) in China.
Journal: European journal of heart failure
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40982271
Summary: This study evaluated the impact of the National Heart Failure Center Accreditation Program in China on heart failure therapy implementation. Results indicated that hospitals participating in the accreditation program demonstrated improved adherence to guideline-directed medical therapy for heart failure patients. The nationwide implementation of standardized heart failure care through accreditation programs can lead to better treatment and outcomes.
Article 5: Dynamic tricuspid regurgitation in heart failure with preserved ejection fraction.
Journal: European journal of heart failure
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40977275
Summary: This study investigated the changes in tricuspid regurgitation severity during exercise in patients with Heart Failure with Preserved Ejection Fraction using invasive hemodynamic exercise testing and echocardiography. The study found that tricuspid regurgitation often worsens during exercise in these patients, correlating with hemodynamic changes, reduced cardiopulmonary reserve, and worse prognosis. These findings highlight the importance of assessing dynamic tricuspid regurgitation during exercise in Heart Failure with Preserved Ejection Fraction for risk stratification and management.
Transcript
Today’s date is September 24, 2025. Welcome to Cardiology Today. Here are the latest research findings.
Article number one. Height May Explain Sex Differences in Systolic Blood Pressure in Older Adults. This study analyzed data from the National Health and Nutrition Examination Surveys, examining older women and men with hypertension. The analysis suggests that differences in height contribute to higher systolic blood pressure values in older women compared to men, potentially explaining lower hypertension control rates in women. These findings highlight the importance of considering height when managing hypertension in older adults, especially in women.
Article number two. Long-Term Impact of Platelet Reactivity and Clinical Risk on Clinical Outcomes in Patients With Coronary Artery Disease: Analysis of the P.T.R.G.-D.E.S. Registry. This study from the P.T.R.G.-D.E.S. registry assessed the interaction between platelet reactivity and clinical risk, as determined by the Thrombolysis in Myocardial Infarction Risk Score for Secondary Prevention, on clinical outcomes after percutaneous coronary intervention. The results showed that high platelet reactivity, combined with high clinical risk scores, was associated with increased adverse clinical events in patients with coronary artery disease treated with drug-eluting stents. This suggests that tailoring antiplatelet therapy based on both platelet function and clinical risk assessment could improve outcomes after percutaneous coronary intervention.
Article number three. Transpulmonary Proteome Gradients Identify Pathways Involved in Pulmonary Vascular Disease Due To Heart Failure. This study investigated transpulmonary protein gradients in patients with Heart Failure with Reduced Ejection Fraction to identify mediators of pulmonary vascular disease. Proteomic analysis revealed distinct protein signatures associated with pulmonary vascular disease development in the setting of heart failure. The identified pathways may represent potential therapeutic targets for preventing or treating pulmonary vascular disease in patients with heart failure.
Article number four. Nationwide implementation of heart failure therapies: National Heart Failure Center Accreditation Program (H.F.-C.A.P.) in China. This study evaluated the impact of the National Heart Failure Center Accreditation Program in China on heart failure therapy implementation. Results indicated that hospitals participating in the accreditation program demonstrated improved adherence to guideline-directed medical therapy for heart failure patients. The nationwide implementation of standardized heart failure care through accreditation programs can lead to better treatment and outcomes.
Article number five. Dynamic tricuspid regurgitation in heart failure with preserved ejection fraction. This study investigated the changes in tricuspid regurgitation severity during exercise in patients with Heart Failure with Preserved Ejection Fraction using invasive hemodynamic exercise testing and echocardiography. The study found that tricuspid regurgitation often worsens during exercise in these patients, correlating with hemodynamic changes, reduced cardiopulmonary reserve, and worse prognosis. These findings highlight the importance of assessing dynamic tricuspid regurgitation during exercise in Heart Failure with Preserved Ejection Fraction for risk stratification and management.
Thank you for listening. Don’t forget to subscribe.
Keywords
systolic blood pressure, Heart Failure with Preserved Ejection Fraction, H.F.-C.A.P., height, heart failure, proteomics, accreditation program, pulmonary hypertension, hypertension, China, pulmonary vascular disease, hemodynamics, older adults, guideline-directed medical therapy, coronary artery disease, tricuspid regurgitation, exercise, Thrombolysis in Myocardial Infarction Risk Score for Secondary Prevention, Heart Failure with Reduced Ejection Fraction, platelet reactivity, percutaneous coronary intervention, drug-eluting stents, transpulmonary gradient, sex differences.
About
Concise summaries of cardiovascular research for professionals.
Subscribe • Share • FollowThe post Height Drives Hypertension in Older Women 09/24/25 first appeared on Cardiology Today.
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