๐ŸŽ™๏ธ Episode 15: Fine-tuning HFpEF: Finerenone Finds Its Footing

20/04/2025 2 min Temporada 1 Episodio 15
๐ŸŽ™๏ธ Episode 15: Fine-tuning HFpEF: Finerenone Finds Its Footing

Listen "๐ŸŽ™๏ธ Episode 15: Fine-tuning HFpEF: Finerenone Finds Its Footing"

Episode Synopsis

Send us a text๐Ÿง  Clinical Problem:HFpEF (Heart Failure with Preserved EF) has lacked effective, proven therapies.Finerenone (non-steroidal MRA) offers new hope.๐Ÿงช FINEARTS-HF Trial:6,000+ patients with EF โ‰ฅ40%, followed for ~32 months.Compared Finerenone vs placebo.๐Ÿ“ˆ Results:โ†“ Heart failure hospitalization significantly.No significant reduction in CV mortality.Hyperkalemia: 9.7% (Finerenone) vs 4.2% (Placebo).๐Ÿงฉ Clinical Takeaway:May offer benefit for HFpEF โ€” especially if SGLT2i also used.Expensive; Spironolactone may be a lower-cost alternative with similar benefit.Important addition to the limited HFpEF toolbox.

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