Cain's parents thought he would be the chosen seed to crush the head of the serpent. Instead, Cain became the seed of the serpent by murdering his own brother and being arrogant towards God. Meanwhile, another brother is born who would be chosen by God.

Sources:
Guzik, David. “Study Guide For Genesis 4.” Blue Letter Bible, 2018, https://www.blueletterbible.org/comm/guzik_david/study-guide/genesis/genesis-4.cfm.
“1892. Hebel.” Strong's Hebrew: 1892. הָ֫בֶל (Hebel) -- Vapor, Breath, Bible Hub, 2004, https://biblehub.com/hebrew/1892.htm.
Armstrong, Stephen. “Genesis 2011 - Lesson 4B.” Verse By Verse Ministry International, 18 Apr. 2011, https://versebyverseministry.org/lessons/genesis_2011_lesson_4b.
“2596. Chanak.” Strong's Hebrew: 2596. חָנַך (Chanak) -- to Train up, Dedicate, Bible Hub, 2004, https://biblehub.com/hebrew/2596.htm.
“5710b. Adah.” Strong's Hebrew: 5710B. Adah -- to Ornament or Deck Oneself, Bible Hub, 2004, https://biblehub.com/hebrew/5710b.htm.
“6751. Tsalal.” Strong's Hebrew: 6751. צָלַל (Tsalal) -- to Be or Grow Dark, Bible Hub, 2004, https://biblehub.com/hebrew/6751.htm.
“5276. Naem.” Strong's Hebrew: 5276. נָעֵם (NAEM) -- to Be Pleasant, Delightful, or Lovely, Bible Hub, 2004, https://biblehub.com/hebrew/5276.htm.
Armstrong, Stephen. “Genesis 2011 - Lesson 4C.” Verse By Verse Ministry International, 2 May 2011, https://versebyverseministry.org/lessons/genesis_2011_lesson_4c.

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