Base by Base

Base by Base

Por: Gustavo Barra
Base by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each episode breaks down key studies and their clinical relevance—one base at a time.

Powered by AI, Base by Base offers a new way to learn on the go. Special thanks to authors who publish under CC BY 4.0, making open-access science faster to share and easier to explore.
244 episodios disponibles

Latest episodes of the podcast Base by Base

Mostrando página 7 de 13

124: Exploring the Omnigenic Architecture of Selected Complex Traits 01/09/2025
123: Dominant‑Negative ATP5F1A Variants Uncouple Complex V and Drive Neurological Disease 31/08/2025
122: Patient Stratification Reveals the Molecular Basis of Disease Co-Occurrences 30/08/2025
121: G-quadruplexes as a Source of Vulnerability in BRCA2-deficient Granule Cell Progenitors and Medulloblastoma 29/08/2025
120: Rare BMAL1 Variants Link the Circadian Clock to Neurodevelopment 28/08/2025
119: G‑Quadruplex Stabilization Triggers Pericentromeric DNA Breaks in B Cells 27/08/2025
118: Cancer cells subvert the primate-specific KRAB zinc finger protein ZNF93 to control APOBEC3B 26/08/2025
117: Pol III–linked polyadenylation fuels SINE RNA accumulation during infection 25/08/2025
116: Cell Type–Specific Purifying Selection of Synonymous mtDNA Variation 24/08/2025
115: A Transcriptomic, Proteomic, and Functional Genetic Atlas Dissects Neurofibromin Function in the Peripheral Nervous System 24/08/2025
114: One-hour extraction-free loop-mediated isothermal amplification HPV DNA assay for point-of-care testing in Maputo, Mozambique 22/08/2025
113: Joint, Multifaceted Genomic Analysis Enables Diagnosis of Ultra-Rare Monogenic Presentations 21/08/2025
112: Local Genetic Sex Differences in Quantitative Traits 20/08/2025
111: A Multimodal Dataset for Precision Oncology in Head and Neck Cancer 19/08/2025
110: Whole-exome sequencing identifies new schizophrenia risk genes 18/08/2025
109: Autocrine Interferon Poisoning: ADAR1–BRCA Synthetic Lethality 17/08/2025
108: Epigenome Editing Reverses HBG Silencing 16/08/2025
107: Genome-wide Association Study Reveals Genetic Links to Pulpal and Apical Diseases 15/08/2025
106: Decoding Brain Maps for Pharmacotranscriptomics 14/08/2025
105: Genome-level Selection as a Universal Marker of Cancer Therapy Resistance 13/08/2025
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