In this episode, Brad reviews a systematic evaluation of local antibiotic delivery systems for infection prophylaxis in implant-based breast reconstruction, highlighting the promising reductions in surgical-site infection and implant loss achieved with biodegradable beads, PMMA antibiotic plates, and continuous postoperative irrigation—while underscoring the evidence gaps that persist due to uniformly retrospective designs (Ann Plast Surg. 2025;95(5):499–505. DOI: 10.1097/SAP.0000000000004416). Lax discusses his recent case series examining the multifaceted challenges of managing hand injuries in patients with significant psychiatric comorbidities, emphasizing the recurrent barriers to care including impaired consent capacity, altered surgical planning, high rates of self-injury, and substantial loss to follow-up that complicate outcomes and demand integrated psychiatric–surgical care pathways (Ann Plast Surg. 2025;95(5):511–515. DOI: 10.1097/SAP.0000000000004503). Ben covers an updated systematic review and meta-analysis evaluating acellular dermal matrix as an adjunct in primary and secondary palatoplasty, detailing how pooled contemporary data demonstrate a significant reduction in postoperative oronasal fistula formation when ADM is incorporated into repair, reaffirming its value as a reliable tool in reconstruction (Ann Plast Surg. 2025;95(5):516–521. DOI: 10.1097/SAP.0000000000004483).   Music credit: Sweet talks by Limuji from freetouse.com

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