Listen "Seeding a Dozen Unicorns & Transforming Healthcare at Home Through Smart Medication Adherence | Kal Vepuri, Founder & CEO of Hero and Brainchild Holdings"
Episode Synopsis
On this episode of WellBuilt, Jon sits down with Kal Vepuri, serial entrepreneur, prolific angel investor, and founder of Hero, for a wide-ranging conversation on investing and building human-first companies and redefining modern healthcare. Kal shares stories from his early years as a curious, nonconforming kid, and how a life-altering accident during a visit to India forced him to confront questions of identity, resilience, healing, and care systems. He made Sweetgreen his first angel investment, eventually backing over 100 startups—more than a dozen of which became unicorns, including Gusto, Coinbase, Oscar, Seatgeek, DuckDuckGo, Astranis, Warby Parker, Dataminr, Reformation, and Arcadia. He later founded Hero, a smart pill dispenser and care platform transforming how families manage medications. The conversation covers: 💊 The origin of Hero: watching his mom juggle dozens of pills, and turning that struggle into an elegant tech solution for families and caregivers. 🧠 The psychology of adherence: why taking your meds is harder than it seems, and how trust, design, and routine shape behavior. 📈 Lessons from angel investing: what Kal looks for in founders, how he spots category-defining products, and why simplicity wins. 🪩 Psychedelic therapy, science-backed wellness, and the shift toward evidence-based modalities that treat the root cause. 🧘🏾♂️ Kal's personal rituals for resilience, including solitude, coaching, and a more grounded approach to leadership. 🌍 How personal loss and cultural complexity shaped his worldview—and his drive to build systems that help people live better, longer lives. 📣 His thoughts on digital health, the GLP-1 craze, longevity hype, and what truly matters in the next wave of care innovation. Enjoy!
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