This episode of Deep Dive explores "Dopamine, Aversion, and the Four Noble Truths in the Age of Technology," explores the intersection of neuroscience and Buddhist philosophy, specifically focusing on how modern technology exploits innate human drives. The author argues that dopamine, often misconstrued as a pleasure chemical, primarily fuels anticipation and craving, a concept mirrored in the Buddhist idea of taṇhā. Conversely, aversion, driven by norepinephrine and glutamate, represents the other side of suffering (dukkha), trapping individuals in a cycle of wanting and fearing. The text emphasizes how social media and app design deliberately amplify these neurochemical loops through mechanisms like variable ratio reinforcement, contributing to addiction and discontent. However, it also presents GABA as a key neurotransmitter for cessation and calm, suggesting that practices like meditation, which increase GABA levels, offer a path toward liberation from these ingrained patterns, aligning with the Buddha's Four Noble Truths.

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