In this week’s episode of The Menopause and Cancer Podcast, Dani speaks with two of the authors behind the new paper, Menopausal hormone therapy for breast cancer patients: what is the current evidence? Professor Jayant Vaidya, Consultant Oncoplastic Breast Surgeon, and Dr Sarah Glynne, GP and menopause specialist.This is the first of a two-part special exploring what this new paper and upcoming MENO-ABC clinical trial could mean for breast cancer survivors curious about HRT or already on HRT.Up until recently, most experts thought a study like this would never happen — but it’s happening.Together, they unpack:What’s new about this paper — and why it matters.The scientific and ethical concept of equipoise (yes, Dani learned a new word!).How the new MENO-ABC trial could change what we know about HRT use after breast cancer.What this research might mean for patients, clinicians, and the future of survivorship care.Next week: Don’t miss part two, where Dani and Dr Sarah Glynne take a deep dive into testosterone use after breast cancer — what we know, what we don’t, and where the conversation is heading.Links & Resources:The paper: https://journals.lww.com/menopausejournal/fulltext/9900/menopausal_hormone_therapy_for_breast_cancer.532.aspxThe trial: https://www.londonbreastcancer.com/meno-abc-trialFind Dr Glynne here https://www.clairemellon.co.uk/dr-sarah-glynneFind Professor Vaidya here https://professorvaidya.co.uk/Watch Dani’s 5-part Youtube series on HRT after breast cancer, start here: https://www.youtube.com/watch?v=heTF5ufX59Y&list=PLsUEBZ4ZwowpAQ1ueFUHlzDvzAtD_hyQr&index=6 Episode Highlights:00:00 Intro08:01 "HRT Debate and Its Impact"09:48 Evidence-Based Breast Cancer Trial13:46 Advances in Breast Cancer Treatment16:43 HRT Risks Post-Breast Cancer20:52 Oestrogen Risks in Cancer Relapse23:17 "Clinical Trial Equipoise Explained"29:00 "Expert Consensus and Criticism"29:47 Collaborative Review Strengthened Research32:52 Breaking Shame Through Conversations36:04 Weighing Risks for Quality Life41:57 "Prioritising Quality Over Longevity"43:08 HRT and Breast Cancer Relapse RiskRead all about HRT after breast cancer in Dani’s book “Navigating Menopause After Cancer’ in chapter 6: Buy it here: https://amzn.eu/d/0uLveeE 

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