Mitochondria are the powerhouses of the cell which function to make ATP and energy. Their role in chronic disease is widely studied and often overlooked. Symptoms and root causes of mitochondrial dysfunction can be difficult to pinpoint in your patients. When it comes to relating this to brain fatigue or thyroid dysfunction, Dr. Datis Kharrazian is an expert. He has written several books and lectured extensively on these topics. In this episode, Dr. Kharrazian outlines his approach to chronic disease using the lost art of the physical exam, laboratory assessments, and a review of current literature. Learn how he uses subtle clues to uncover root causes and what he does to improve patient outcomes.  “One of your best windows to assess mitochondrial compromise is to look at the brain.” – Dr. Datis Kharrazian Today on The Lab Report: 2:40 Meet Dr. Datis Kharrazian 10:10 Mitochondrial dysfunction and how it affects the brain 13:00 Symptoms, causes, and treatment of brain fatigue 19:00 The functional neurological exam 21:00 Stimulating neurologic mitochondrial biogenesis 22:50 Working up brain fatigue with functional labs and physical exam 28:05 Functional medicine approach to autoimmune thyroid disease 31:32 Intestinal permeability, gluten, and lectins in autoimmunity 39:00 Using stool testing and food antibody testing to assess immune tolerance 43:40 Kharrazian explains his extensive new patient work up 48:35 The Kharrazian Institute 53:25 The Fireball Additional Resources: Kharrazian Resource Center Kharrazian Institute Why Isn't My Brain Working? Why Do I Still Have Thyroid Symptoms When My Lab Tests Are Normal? Immunological Reactivity Using Monoclonal and Polyclonal Antibodies of Autoimmune Thyroid Target Sites with Dietary Proteins Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.  See omnystudio.com/listener for privacy information.

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