Total Synthesis of Maximiscin

Total Synthesis of Maximiscin

The Cyclo Edition

07/09/2020 8:00AM

Episode Synopsis "Total Synthesis of Maximiscin"

In this episode we discuss the total synthesis of (–)-maximiscin reported by the Baran lab. The route takes advantage of a convergent fragment coupling strategy with a late-stage formation of the central pyridone ring.  DOI: https://doi.org/10.1021/jacs.0c03202

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