Total Synthesis of Maximiscin

07/09/2020 37 min Temporada 2 Episodio 1

Listen "Total Synthesis of Maximiscin"

Episode Synopsis

In this episode we discuss the total synthesis of (–)-maximiscin reported by the Baran lab. The route takes advantage of a convergent fragment coupling strategy with a late-stage formation of the central pyridone ring. 

DOI: https://doi.org/10.1021/jacs.0c03202