Therapeutic brain-computer-interfaces for glioblastoma, with Dr Elise Jenkins

10/02/2025 37 min Episodio 20
Therapeutic brain-computer-interfaces for glioblastoma, with Dr Elise Jenkins

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Episode Synopsis

Electrical monitoring and stimulation could revolutionise diagnosis and treatment for some of the most aggressive brain cancers and intractable neurological diseases.In glioblastoma, a particularly aggressive brain tumour that is hard to treat and almost invariably fatal, the impacts of an effective treatment would be huge.My guest in this episode, Dr Elise Jenkins, is working with a new class of therapeutic brain-computer-interface (BCI) that can measure and disrupt neural signalling within the body. With this technology she and her team are creating breakthroughs in new materials and electronics to develop safe, minimally invasive interfaces to interact with the complex biology of the brain. That will lead to earlier detection of new tumours, and could pave the way for new treatments. Elise shares her journey from aspiring medical doctor to electrical engineer to leading a neurotechnology startup. She discusses the many difficult challenges of engineering tiny bioelectronic devices, and the importance of understanding brain activity in cancer progression for them to be a success.We also touch on regulatory hurdles, funding strategies, and the future potential of the technology in both cancer and non-cancer applications.Elise and her team are looking to create a new approach to healthcare which will change the lives of millions.“We're looking at how to slow down cancer growth.” – Elise JenkinsYou’ll hear about:01:06 - Elise Jenkins and OptoBioSystems02:30 - Elise's Journey into Science and Engineering05:42 - Understanding Bioelectronics and Neural Interfaces09:01 - Exploring Glioblastoma and Its Challenges12:18 - Measuring Brain Activity and Cancer Progression16:30 - The Role of Implants in Cancer Treatment19:14 - Engineering Challenges in Medical Devices22:57 - Wireless Power and Data Transmission Innovations25:20 - Regulatory Considerations for Medical Devices28:14 - Future Directions and Broader Applications33:24 - Funding and Company DevelopmentConnect with Elise Jenkins: LinkedIn - https://www.linkedin.com/in/elise-jenkins-/Opto - https://www.opto.bio/Find out about opportunities with Opto - https://www.opto.bio/teamConnect with me:LinkedIn: https://www.linkedin.com/in/markdavison100/ If you need any lab equipment:Grant Instruments: https://www.grantinstruments.com/ Grant Instruments on LinkedIn: https://www.linkedin.com/company/grant-instruments-cambridge-ltd/ 

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