Ovaries, Menopause, and Genomics with Dr Stasa Stankovic

18/10/2024 45 min Episodio 15
Ovaries, Menopause, and Genomics with Dr Stasa Stankovic

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Episode Synopsis

This episode went live on World Menopause Day.Menopause is an inevitable aspect of life for half of the global population, but one that requires far more study. New genomic insights could empower women with better reproductive choices and insights into likely future health.In this episode, I talk with Dr Stasa Stankovic. She has a PhD in Genomic Medicine from Cambridge University, and is on a mission to reshape the future of women's health by developing, and eventually commercialising, prediction tools and next generation therapeutics for female reproductive disorders.We discuss the complexities of female reproductive health, particularly focusing on ovarian ageing and menopause. We also explore the genetic factors influencing menopause timing, and the importance of understanding reproductive health beyond fertility.Stasa shares her collaborative work on large-scale genomics, using samples from the UK Biobank to conduct genome-wide association studies (GWAS). These have highlighted many genes associated with menopause and thus pave the way for potential new diagnostic techniques and therapeutic interventions to give women greater control of their reproductive health.Menopause affects every woman, but also indirectly impacts husbands, partners, colleagues and friends. The work Stasa and her colleagues are doing will have implications not just for women but for all of us.“We need to empower women with knowledge.” – Stasa Stankovic You’ll hear about:01:37 - Stasa's area of research04:14 - Why the science behind menopause is so important07:36 - The ovarian reserve and what that means12:26 - Contributing factors to menopause17:24 - The key findings of the genome-wide association (GWAS) study21:21 - Getting the right targets for intervention27:05 - The challenge of finding animal models for menopause28:22 - Turning lab science into commercial science31:40 - Stasa on the choices that women have38:38 - Is gene intervention possible? Connect with Stasa:LinkedIn - https://www.linkedin.com/in/stasa-stankovic-93723a137/ OvartiX - https://ovartix.com/  Connect with me:LinkedIn: https://www.linkedin.com/in/markdavison100/  If you need any lab equipment:Grant Instruments: https://www.grantinstruments.com/  Grant Instruments on LinkedIn: https://www.linkedin.com/company/grant-instruments-cambridge-ltd/ 

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