In this episode, we discuss recombinant proteins: what are they and what are they used for? BioTechniques Editor Tristan Free speaks to Amy Sheng, Technical Account Manager at Sino Biological, who explains the history of recombinant proteins and how protein modeling techniques such as AlphaFold are changing their development. Find out how monoclonal antibodies have been used through the COVID-19 pandemic and how we may overcome challenges in production, upscaling and more in this episode of Talking Techniques. Contents:Introduction 00:00-01:26What are recombinant proteins and what are they used for? 01:26 – 02:42How were they first developed? 02:42 – 03:50Since initial development has recombinant antibody development progressed today? 03:50 – 05:57What are the advantages of utilizing the more traditional mouse monoclonal antibodies? 05:57 – 07:11Are recombinant antibodies used in more specialist applications and are they more likely to be used in therapeutics? 07:11 – 09:47How have AI systems like AlphaFold impacted the development of recombinant antibodies? 09:47 – 12:07How has antibody production changed and what’s next? 12:07 – End  Hosted on Acast. See acast.com/privacy for more information.

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