Bioengineering a Kidney Chip for Better Safer and Faster Drug Development

25/09/2024 1h 11min

Listen "Bioengineering a Kidney Chip for Better Safer and Faster Drug Development"

Episode Synopsis

Catherine Yeung, Pharm.D., Ph.D., M.P.H., discusses groundbreaking advancements in kidney-on-a-chip technology, emphasizing its potential to revolutionize human health. She delves into the role of environmental toxins, such as okra toxin A, microplastics, and plasticizers, in contributing to chronic kidney disease, particularly in regions with specific dietary practices. Yeung also addresses the challenges of replicating adult kidney cells from stem cells, which often retain a fetal phenotype, and underscores the value of stem cell-derived models for genetic manipulation and disease research. Additionally, she highlights the increased risk of kidney stones in astronauts post-spaceflight and the broader implications of organ-on-chip technology for studying therapies and diseases. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39458]

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