Status epilepticus is traditionally defined as a seizure lasting ≥5 minutes or recurrent seizures without return to baseline in between. It is a neurologic emergency associated with increased morbidity and mortality the longer it persists. Some complications include cardiac arrhythmias, respiratory failure, aspiration pneumonia, and recurrent status epilepticus. The established treatment paradigm includes first line treatment with benzodiazepines (midazolam IM, lorazepam IV, diazepam IV). Second line treatments include antiepileptics (fosphenytoin, levetiracetam, valproate). Third line treatments include anesthetic agents (propofol, ketamine, midazolam infusions).
The post Midazolam vs Ketamine as Second Line in Status Epilepticus appeared first on REBEL EM - Emergency Medicine Blog.

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