OSTEORADIONECROSIS** Cause – reduced blood supply to the radiation site QN Factors – surgery at radiation site – infection by staphylococcus C/F – sequestrum – deadbone (3H hypocellular, hypovascular, hypoxic tissue and Bone) - invulcrum – living bone Prevention – surgical procedure before 6 weeks is best (1 and ½ month) Other methods – surgical procedure 4 months after stoppage of radiation therapy RCT is not contra- indicated Management :-o hyperbaric O2 therapy --> 100% O2(also used in diffusion hypoxia) [best management]o sequestrctomyo resection , Hemimandibulectomy } also done

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