NK - 1 Antagonist Drug Interactions

06/02/2020 17 min
NK - 1 Antagonist Drug Interactions

Listen "NK - 1 Antagonist Drug Interactions"

Episode Synopsis

Drug-drug interactions are a key consideration when determining which NK-1 antagonist to use in patients receiving highly emetogenic chemotherapy. We discuss the issues for (fos)aprepitant, netupitant, & rolapitant.

A nice aprepitant review (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595939/) and the case for an aprepitant-vincristine interaction (https://doi.org/10.1177/1078155219870840).