Listen "45 Software deep dive: Enterobase"
Episode Synopsis
We chat with Nabil about EnteroBase, and learn about the background to the project, the general benefits of the platforms and some of the strange quirks users might encounter. EnteroBase is an integrated software environment that supports the identification of global population structures within several bacterial genera that include pathogens.
Papers:
Mentioned PLOS genetics paper:
Alikhan et al. (2018) A genomic overview of the population structure of Salmonella. PLoS Genet 14 (4): e1007261 https://doi.org/10.1371/journal.pgen.1007261
Paper describing Enterobase and the genome fishing expeditions:
Zhou et al. (2020) The EnteroBase user's guide, with case studies on Salmonella transmissions, Yersinia pestis phylogeny and Escherichia core genomic diversity. Genome Res. 30:138-152. https://doi.org/10.1101/gr.251678.119
rMLST is described in: Jolley et al. 2012 Microbiology 158:1005-15. https://doi.org/10.1099/mic.0.055459-0
Resources
Enterobase: http://enterobase.warwick.ac.uk/
PubMLST https://pubmlst.org/
About EnteroBase schemes: https://enterobase.readthedocs.io/en/latest/enterobase-tutorials/deeper-lineages.html
Software:
Enterobase toolkit and background software: https://github.com/zheminzhou/EToKi
Errata.
Jay Hinton’s Salmonella is a ST313 (D23580), not ST131 (I always mix the numbers up -- Nabil)
Papers:
Mentioned PLOS genetics paper:
Alikhan et al. (2018) A genomic overview of the population structure of Salmonella. PLoS Genet 14 (4): e1007261 https://doi.org/10.1371/journal.pgen.1007261
Paper describing Enterobase and the genome fishing expeditions:
Zhou et al. (2020) The EnteroBase user's guide, with case studies on Salmonella transmissions, Yersinia pestis phylogeny and Escherichia core genomic diversity. Genome Res. 30:138-152. https://doi.org/10.1101/gr.251678.119
rMLST is described in: Jolley et al. 2012 Microbiology 158:1005-15. https://doi.org/10.1099/mic.0.055459-0
Resources
Enterobase: http://enterobase.warwick.ac.uk/
PubMLST https://pubmlst.org/
About EnteroBase schemes: https://enterobase.readthedocs.io/en/latest/enterobase-tutorials/deeper-lineages.html
Software:
Enterobase toolkit and background software: https://github.com/zheminzhou/EToKi
Errata.
Jay Hinton’s Salmonella is a ST313 (D23580), not ST131 (I always mix the numbers up -- Nabil)
More episodes of the podcast Micro binfie podcast
148 - NextFlow debate 3
13/11/2025
147 - NextFlow debate 2
30/10/2025
146 - NextFlow debate 1
16/10/2025
145 - micro binfie Pathoplexus part 2
25/09/2025
144 - micro binfie Pathoplexus part 1
11/09/2025
142 - Microbinfie - genomeqc
07/08/2025
140 Exploring Clinical Metagenomics
03/07/2025
139 Lassa virus genomics
19/06/2025
138 Decoding Tetracycline Resistance in MRSA
16/01/2025
ZARZA We are Zarza, the prestigious firm behind major projects in information technology.