Drs Anne Cross and Scott Newsome discuss new horizons in MS treatment strategies, including the TREAT-MS trial and shared decision-making for optimal patient care. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002606. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.  Resources Multiple Sclerosis https://emedicine.medscape.com/article/1146199-overview Interferon Beta and Glatiramer Acetate Therapy https://pubmed.ncbi.nlm.nih.gov/23264098/ Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial (TREAT-MS) https://www.clinicaltrials.gov/study/NCT03500328 Initiation Patterns of Disease-Modifying Therapies for Multiple Sclerosis Among US Adults and Children, 2001 Through 2020 https://pubmed.ncbi.nlm.nih.gov/37428482/ What We Learned From the History of Multiple Sclerosis Measurement: Expanded Disability Status Scale https://pubmed.ncbi.nlm.nih.gov/30692861/ The Multiple Sclerosis Functional Composite Measure (MSFC): An Integrated Approach to MS Clinical Outcome Assessment. National MS Society Clinical Outcomes Assessment Task Force https://pubmed.ncbi.nlm.nih.gov/10467383/ Long-term Efficacy and Safety of Alemtuzumab in Participants With Highly Active MS: TOPAZ Clinical Trial and Interim Analysis of TREAT-MS Real-World Study https://pubmed.ncbi.nlm.nih.gov/39935588/ Imaging Outcome Measures for Progressive Multiple Sclerosis Trials https://pubmed.ncbi.nlm.nih.gov/29041865/ Current Use of Fluid Biomarkers as Outcome Measures in Multiple Sclerosis (MS): A Review of Ongoing Pharmacological Clinical Trials https://pubmed.ncbi.nlm.nih.gov/38117403/ Patient-reported Disability Progression Outcomes Among Patients With Multiple Sclerosis: Results of an Outcomes-Based Agreement https://pubmed.ncbi.nlm.nih.gov/39471272/ Insights for Healthcare Providers on Shared Decision-making in Multiple Sclerosis: A Narrative Review https://pubmed.ncbi.nlm.nih.gov/38180727/ Practice Guideline Update Summary: Vaccine-Preventable Infections and Immunization in Multiple Sclerosis: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology https://pubmed.ncbi.nlm.nih.gov/31462584/

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