Women, Psilocybin, and Transformation: Hormones and Healing with Jennifer Chesak

12/01/2025 45 min

Listen "Women, Psilocybin, and Transformation: Hormones and Healing with Jennifer Chesak"

Episode Synopsis

In episode 55 of Medicine with the Medals, Michele welcomes Jennifer Chesak, author of The Psilocybin Handbook for Women. Jennifer shares her journey into the world of psilocybin, blending her expertise in women's health and psychedelics to uncover how psilocybin uniquely interacts with the female body.
Together, they discuss the importance of understanding hormonal cycles, the need for women-specific microdosing protocols, and the groundbreaking research on psilocybin’s effects on mood, trauma, and menopause.
Jennifer also sheds light on the intersection of indigenous wisdom and modern science, emphasizing the importance of honoring the roots of these sacred medicines. From personal experiences to scientific insights, this conversation is packed with actionable knowledge and inspiring perspectives.
Whether you're new to psychedelics or a seasoned explorer, this episode offers a fresh, empowering lens on the transformative potential of psilocybin for women.
Chapters:

00:00 - Introduction: Medicine with the MedalsMichelle introduces the episode, explains Mark's absence, and welcomes Jennifer Chesak, author of The Psilocybin Handbook for Women.

02:10 - Jennifer’s Journey to PsilocybinJennifer shares her background as a journalist and author, her fascination with psilocybin, and her personal experiences with this natural psychedelic.

06:45 - Microdosing: Intuition vs. ProtocolsA discussion on microdosing psilocybin, including Jennifer's personal approach and the benefits of structured protocols.

11:30 - Women and Psilocybin: Hormonal ImpactsJennifer explains how psilocybin interacts with the female body, the role of hormones, and the potential need for female-specific microdosing protocols.

19:05 - Psilocybin and MenopauseExploring psilocybin’s impact on perimenopause and menopause symptoms, from mood changes to trauma and behavior modifications.

26:40 - Indigenous Wisdom and PsilocybinJennifer highlights the importance of honoring indigenous traditions, set and setting, and the ethical considerations surrounding psilocybin use.

36:25 - Functional Mushrooms and PsilocybinA conversation about integrating functional mushrooms like lion’s mane and cordyceps into wellness practices alongside psilocybin.

41:15 - Jennifer’s Book and Where to Find ItDetails about The Psilocybin Handbook for Women, Jennifer’s background in publishing, and where to purchase signed copies.

45:00 - Final Thoughts and Future CollaborationMichelle and Jennifer discuss their shared love for psilocybin and possibilities for future collaborations.


Learn more about Jennifer Chesak.
Find the best microdosing products for women at Mama Dose
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