In this week's episode, we talk about how targeting a specific immune cell called an eosinophil may help lower the burden of COPD (chronic obstructive pilmonary disease). We explore the epidemiology, pathophysiology, and treatment options for COPD, including targeting the eosinophil pathway.References:Bhatti, M. S. (1999). A historical look at chlorofluorocarbon refrigerants. ASHRAE Transactions, 105, 1186. https://www.osti.gov/biblio/20002388Narendra, D. K., & Hanania, N. A. (2019). Targeting IL-5 in COPD. International journal of chronic obstructive pulmonary disease, 1045-1051. https://www.tandfonline.com/doi/full/10.2147/COPD.S155306World Health Organization. (6 November, 2024). Chronic obstructive pulmonary disease (COPD). [Website, accessed 4 November, 2025]. https://www.who.int/news-room/fact-sheets/detail/chronic-obstructive-pulmonary-disease-(copd)Barnes, P. J. (2019). Inflammatory endotypes in COPD. Allergy, 74(7), 1249-1256. https://onlinelibrary.wiley.com/doi/full/10.1111/all.13760Dixon F. J. (Ed.). (1987). Advances in immunology (Vol. 39). Academic Press. https://www.google.com/books/edition/Advances_in_Immunology/GXpByqkfZNcC

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