The podcast defines agoraphobia as an anxiety disorder characterised by significant fear in open space situations where escape is difficult. It outlines multiple potential causes, including genetic predisposition, past trauma, cognitive biases, biological factors, personality traits, learned behaviours, environmental stressors, and its close link to panic disorder. The text also details various treatment approaches, such as Cognitive Behavioural Therapy (CBT), gradual exposure, mindfulness, medication, and the importance of support systems, journaling, and self-care, offering resources for each method.

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