The inspirational Dr. Sangita Agarwal (Rheumatologist) & Dr. Boris Lams (Respiratory), inflammatory lung specialists, take us through our emerging understanding of the complications of COVID-19: HyperinflammationARDSHaemophagocytic lymphohistiocytosis (HLH)IntroductionBackground to the lung inflammation service (03:02)The secret to the dynamic duo and navigating disagreement (05:15)HLH: Haemophagocytic lymphohistiocytosisHLH: what is it and why is it relevant in COVID-19 "The power of the immune system" (06:40) Common triggers of HLH (08:40)Screening for HLH and The H score (09:08)Investigations for HLH and the return of ferritin (13:43) ARDSThe basics of ARDS. Subtypes: "normal & atypical" (16:45)HLH and ARDS (19:47)COVID driving ARDS and the possible subtypes of "COVID ARDS" (20:40)Hyperinflammatory COVID-19 & TherapiesSteroids and severe COVID-19 (28:05) Potential therapies targeting the abnormal host response (32:01)Lung fibrosis (38:54)ConclusionsTake-home points (44:20)TIME IS LUNG! (46:12)Buzzwords#Trialtastic#Inflammologist#TimeIsLung---------------------------------------------------------- Get in touch! @JournalSpotting or [email protected]’d love to hear from you: what you thought of the show, what you would like to hear, and if you have any articles that you would like us to share with the general medicine world! A wise man at your ARCP once said: "It didn't happen unless you've filled in a feedback form". (But seriously, we'd love to hear what you think!)Support the showVisit the website on www.journalspotting.com. Follow us on Twitter @JournalSpotting.Email us on [email protected] our JournalClub App on https://journalclub.messly.comShare us with all your colleagues!

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