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Listen "JNP Micro Podcasts: Aging and Subcortical Gray Matter Volume"
Episode Synopsis
In this podcast Dr. Peka Christova of The Neuroimaging Research Group, Brain Sciences Center discusses the recently published Short Report titled "Changes of gray matter volumes of subcortical regions across the lifespan: a Human Connectome Project study."
NEW & NOTEWORTHY Christova et al. report mixed effects of age on subcortical grey matter volume (GMV) during lifespan (n = 2458, 5-90 yr old, 1113 male, 1345 female). Striatal and cerebellar GMVs decreased linearly with age, more steeply in males. In contrast, GMVs of the amygdala, pallidum, thalamus, ventral diencephalon, and brainstem changed in a quadratic fashion, increasing first and decreasing afterward, with males peaking earlier than females in all regions but the brainstem where they peaked at nearly the same time.
Article Citation:
Changes of gray matter volumes of subcortical regions across the lifespan: a Human Connectome Project study
Peka Christova and Apostolos P. Georgopoulos
Journal of Neurophysiology 2023 130:5, 1303-1308
NEW & NOTEWORTHY Christova et al. report mixed effects of age on subcortical grey matter volume (GMV) during lifespan (n = 2458, 5-90 yr old, 1113 male, 1345 female). Striatal and cerebellar GMVs decreased linearly with age, more steeply in males. In contrast, GMVs of the amygdala, pallidum, thalamus, ventral diencephalon, and brainstem changed in a quadratic fashion, increasing first and decreasing afterward, with males peaking earlier than females in all regions but the brainstem where they peaked at nearly the same time.
Article Citation:
Changes of gray matter volumes of subcortical regions across the lifespan: a Human Connectome Project study
Peka Christova and Apostolos P. Georgopoulos
Journal of Neurophysiology 2023 130:5, 1303-1308
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