ZARZA We are Zarza, the prestigious firm behind major projects in information technology.
Listen "Positive Negatives - genistein and resveratrol"
Episode Synopsis
The first podcast of 2022 discusses two papers with negative outcomes and explores the importance of sharing such results for patients and families and clinicians working with rare disease. Dr Nicoline Løkken discusses her work with resveratrol in mitochondrial myopathies (from 5m 18s) and Dr Arunabha Ghosh and Professor Brian Bigger talk about the use of genistein in Sanfilippo syndrome (from 10m 38s).
No effect of resveratrol in patients with mitochondrial myopathy: A cross-over randomized controlled trial
Nicoline Løkken, et al
https://doi.org/10.1002/jimd.12393
High dose genistein in Sanfilippo syndrome: A randomised controlled trial
Arunabha Ghosh, et al
https://doi.org/10.1002/jimd.12407
No effect of resveratrol in patients with mitochondrial myopathy: A cross-over randomized controlled trial
Nicoline Løkken, et al
https://doi.org/10.1002/jimd.12393
High dose genistein in Sanfilippo syndrome: A randomised controlled trial
Arunabha Ghosh, et al
https://doi.org/10.1002/jimd.12407
More episodes of the podcast JIMD Podcasts
Shortcast: Liver Directed Rx don’t change biochemistry nor Leukodystrophy in Biallelic HMBS Variants
30/12/2025
Sixty Years of Metabolic Medicine: A Conversation with Jean-Marie Saudubray and Manuel Schiff
23/12/2025
Shortcast: Exploratory Study on the Challenges of Newborn Screening for Lysosomal Storage Disorders
25/11/2025
IMD Research Round-Up: Mitochondrial disease
11/11/2025
In God we trust