The Sequential Organ Failure Assessment (SOFA)-2 Score

29/10/2025 15 min
The Sequential Organ Failure Assessment (SOFA)-2 Score

Listen "The Sequential Organ Failure Assessment (SOFA)-2 Score"

Episode Synopsis

SOFA-2, validated in more than 3 million intensive care unit (ICU) patients, incorporates contemporary organ support treatments, showing strong predictive validity for ICU mortality in diverse international settings. Coauthor Mervyn Singer, MD, joins JAMA Associate Editor Christopher W. Seymour, MD, MSc, to discuss. Related Content: Rationale and Methodological Approach Underlying the Development of the Sequential Organ Failure Assessment (SOFA)–2 Score Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score A Revision to Organ Failure Assessment in Critically Ill Patients

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