Unseen Reservoirs, Unseen Risks: Integrating Wastewater Surveillance with Patient-Level Insights into C. auris Spread

10/12/2025 18 min Temporada 3 Episodio 173
Unseen Reservoirs, Unseen Risks: Integrating Wastewater Surveillance with Patient-Level Insights into C. auris Spread

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Episode Synopsis

In this episode, Martin talks to Dr Jon Otter, Director of Infection Prevention and Control at Guy's and St Thomas' Hospital in London, UK. We examine two complementary pieces of work that provide further insight into Candidozyma auris transmission in acute hospitals. The first demonstrates, for the first time in the UK, that ward-level wastewater reliably mirrors patient colonisation and can reveal genetically related outbreak strains using culture and PCR. The second, a case–control study, identifies clinical and environmental risk factors that shape colonisation, highlighting the significance of shared patient equipment.
The paper can be found here: Davidson HC, Griffin AE, Symes L, Laing KG, Witney AA, Gould K, et al. Detection of Candidozyma (formerly Candida) auris from ward wastewater during an outbreak using culture and molecular methods. J Hosp Infect 2025. https://doi.org/10.1016/j.jhin.2025.10.024 
A copy of the poster can be downloaded here

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