Acetaminophen is the leading cause of acute liver failure in developed countries, and even normal doses have been shown to stress the liver in otherwise healthy adults Tylenol PM combines acetaminophen with diphenhydramine, creating risks not only for liver damage but also for memory loss and dementia Long-term acetaminophen use in older adults is linked to gastrointestinal bleeding, ulcers, high blood pressure, heart failure, and chronic kidney disease The drug harms your body by depleting glutathione, your master antioxidant, and disrupting protective systems that safeguard your stomach, heart, and kidneys Safer pain relief strategies include natural options like curcumin, magnesium, and lifestyle practices, along with boosting glutathione levels through foods and, in emergencies, N-acetylcysteine (NAC)

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