A new clinical analysis based on the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) found that older adults taking a daily cocoa extract supplement saw an 8.4% annual drop in high-sensitivity C-reactive protein (hs-CRP), a key marker of chronic inflammation The supplement provided 500 milligrams of cocoa flavanols daily, including 80 milligrams of (-)-epicatechin, which is the same bioactive compound found naturally in cacao Researchers said this anti-inflammatory effect may help explain a 27% lower risk of cardiovascular mortality previously observed in the larger COSMOS trial Taking a cocoa flavanol supplement appears to support vascular and immune health by calming NF-κB signaling and improving endothelial function Unlike dark chocolate, standardized cocoa extract supplements are free of sugar and fat, delivering clinically studied doses in capsule form

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