This episode reviews the identification and management of patients with salicylate toxicity.



https://media.blubrry.com/coreem/content.blubrry.com/coreem/Podcast_Episode_147_0_Final_Cut.m4a



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Tags: Aspirin, Salicylate, Toxicology





Show Notes
Take Home Points

Always consider salicylate toxicity:

In patients with tachypnea, hyperpnea, AMS and clear lungs
In the presence of an anion gap metabolic acidosis with a respiratory alkalosis


Treat salicylate toxicity by alkalinizing the blood and urine to increase excretion
Avoid intubation until absolutely necessary. If you do have to intubate, minimize apneic time and consider awake intubation and nake sure your ventilator settings match the patient’s necessary high minute ventilation
Think about chronic salicylate toxicity in unexplained altered mental status, tachypnea or metabolic acidosis in elderly
Know indications for hemodialysis in salicylate toxic patients



REBEL EM: Salicylate Toxicity
LITFL: Salicylates
Wiki EM: Salicylate Toxicity
Rebel EM: Acute Salicylate Toxicity, Mechanical Ventilation, and Hemodialysis
Mosier JM et al. The Physiologically Difficult Airway. The western journal of emergency medicine. 16(7):1109-17. 2015. PMID: 26759664

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