Pour the coffee—things are about to get clinical. In this episode, Poppy and Kae tackle one of the most complex and test-heavy topics in pathophysiology: cancer. Not zodiac season—real, clinical cancer. We break down the big scary terms from McCance and Huether’s Pathophysiology, 9th Edition (Chapter 12) into concepts you’ll actually remember when exam day comes.From tumors vs. neoplasia vs. cancer, to benign vs. malignant metaphors (polite houseguests vs. snack-stealing freeloaders), we lay the foundation before diving into the genetics: oncogenes (gas pedal), tumor suppressors (brakes), and caretaker genes (the repair crew). You’ll also meet the infamous Philadelphia chromosome and the full “hallmarks of cancer” bingo card, from cheating death to throwing metabolic ragers (hello, Warburg effect).Expect mnemonics, metaphors, a few questionable analogies, and plenty of caffeine as we translate the molecular chaos into nurse-ready knowledge. By the end, you’ll not only understand how cancer cells go rogue, but also how to spot the exam questions coming.Because in nursing, cancer isn’t just a diagnosis—it’s a whole new way of thinking about growth, invasion, and what happens when the rules get thrown out the window.

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